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Publications

Below you will find a list of publications which gives an impression of areas of special expertise in BioAdvice. Copies can be obtained by contacting kdj@bioadvice.dk.

  • Damm Jørgensen, K.: The Pharmacology of a New Hypoglycaemic Agent N-4[2-(2.3dihydrobenzo(b)furan-7-carboxamido)-ethyl)-benzenesulphonyl]-N'-cyclohexylurea (NOVO CS 476.). I. Pharmacological Studies on the Hypoglycaemic Effect. Acta Pharmacol. et toxicol, 1977, 40, 216-226.
  • Damm Jørgensen, K.: The Pharmacology of a New Hypoglycaemic Agent N-4[2-(2.3dihydrobenzo(b)furan-7-carboxamido)-ethyl)-benzenesulphonyl]-N'-cyclohexylurea (NOVO CS 476.). II. Pharmacological Studies on the Mechanism of Action. Acta Pharmacol. et toxicol. 1977, 40,227-233.
  • Damm Jørgensen, K.: The Pharmacology of a New Hypoglycaemic Agent N-4[2-(2.3dihydrobenzo(b)furan-7-carboxamido)-ethyl)-benzenesulphonyl]-N'-cyclohexylurea (NOVO CS 476.). III. General Pharmacological Studies. - Acta Pharmacol. et toxicol. 1977, 40. 234-240.
  • Damm Jørgensen, K.: Actions of Fenfluramine on Glucose Uptake in Vitro and in Vivo. Acta Pharmacol. et toxicol. 1977, 40. 401-417.
  • Damm Jørgensen, K.: Diabetes Mellitus hos hund. Dansk Veterinærtidsskrift. 1979, 62, 221-232.
  • Thimm, L., Jørgensen, K.H. and Damm Jørgensen, K.: Pancreatic Spasmolytic Polypeptide (PSP). II. Radioimmunological determination of PSP in porcine tissues, plasma and pancreatic juice. Regul. Pept., 1982, 3, 221-230.
  • Damm Jørgensen, K., Diamant, B., Jørgensen, K.H. and Thimm, L.. Pancreatic Spasmolytic Polypeptide (PSP): III. Pharmacology of a New Porcine Polypeptide with Spasmolytic and Gastric Acid Secretion Inhibitory Effects, Regul. Pept., 1982, 3. 231-243.
  • Damm Jørgensen, K., WoIffbrandt, K.H. and Weis, J.U.: Preclinical Studies on Human Insulin. Il. General Pharmacological Studies. Acta Pharmacol. et toxicol. 1983. 52, 268-272.
  • Damm Jørgensen, K., Weis, J.U., and Diamant, B.: Dissociation of the Spasmolytic and Metabolic effects of Glucagon. Eur. J. Pharmacol. 1983, 90, 315-323.
  • Damm Jørgensen, K. and Diamant, B.: Inhibitory Effect of Aprotinin on Gastric Acid Secretion. Scand. J. Gastroenterol. 1984,19,999-1006.
  • Wolffbrandt, K.H., Damm Jørgensen, K., Moody, A.J-, and Pedersen, P.C.: The Effects of Porcine GIP on Insulin Secretion and Glucose Clearance in the Pig. Horm. Metab. Res., 1986,18,159-162.
  • Christensen, T., Hansen, J.W., Pedersen, J., Dalbøge, H., Carlsen, S., Jensen, E.B.,Damm Jørgensen, K., Dinesen, B., Nilsson, P., Sørensen, H.H., Thomsen, J. and Kappelgaard, A.-M.: Biosynthetic Human Growth Homone Identical to Authentic Material. Advanced Drug Delivery System for Peptides and Proteins. IIlum, L., Davis, S.S., Tomlinson, E.1986. In press.
  • Damm Jørgensen, K.: Comparison of the Pharmacological Properties of Pituitary and Biosynthetic Human Growth Hormone. Dernonstration of Antinatriuretic/Antidiuretic and Barbital Sleep Effects of Human Growth Hormone in Rats. Acta Endocrinol. 1987, 114,124- 131.
  • Hansen, F.B.. Clausen I.G., Dath, B., Jensen, E.B., Johansen, B.R., Jonassen, I., Junker, F., Jørgensen, K.D., Meyn, G., Petersen, J. and Balschmidt, P.: Insulin analogues - Potentials for Improving Diabetes Treatment. Bayer AG Centenary Symposium. Diabetes Mellitus:Therapy- Edinburgh, U.K., May 25-28,1988. Editors: Creutzfeldt, W. and Lefebvre,P. Springer-Verlag. 155-163.
  • Dalbøge, H., Madsen, B., Damm Jørgensen, K. and Carlsen, S.: Assessment of Risks in Connection with Use of a Recombinant E. Coli Strain for Production of Human Growth Hormone. Danish Medical Bulletin 1988. 35. 84-91.
  • Thorlacius-Ussing, 0., Flyvbjerg, A., Damm Jørgensen, K., and Ørskov, H.: Growth Hormone Restores Normal Growth in Selenium-treated Rats without Increase in Circulating Somatomedin C. Acta Endocrinol. 1988, 177, 65-72.
  • Damm Jørgensen, K., Svendsen, 0., Greenough, R-J., Kallesen, T., Goburdbun, R., Skydsgaard, K., Finch, J., Dinesen, B., and Nilsson P.: Biosynthetic Human Growth Hormone, Subchronic Toxicity Studies in Rats and Monkeys. Pharmacol. Toxicol. 1988, 62, 329-333.
  • Damm Jørgensen, K., Monrad, J.D., Brøndum, L., and Dinesen, B.: Pharmacokinetics of Biosynthetic and Pituitary Human Growth Hormones in Rats. Pharmacol. Toxicol. 1988. 63. 129-134.
  • Damm Jørgensen, K., Jensen, S., and Ørskov, H.: Effects of Growth Hormone Dosing on Ultimate Weight and Length of XO Mice. Pharmacol. Toxicol. 1989, 64. 434-439.
  • Holmberg Jørgensen, P., Torp Andreasen, T. and Damm Jørgensen, K.: Growth Hormone Influences Collagen Deposition and Mechanical Strength of Intact Rat Skin. A dose-response study. Acta Endocrinol. 1989, 120,.767-772.
  • Damm Jørgensen, K., and Nowak, J.: Interaction of Human Growth Hormone and Gonadotrophins on the Function of Rat Ovaries. Pharmacol. Toxicol. 1989. 65. 278-281.
  • Everts, M. E., Dørup, I., Flyvbjerg, A., Marshall, S. M., and Jørgensen, K.D.: Na+-K+ pump in rat rnuscle: Effects of hypophysectomy, growth hormone, and thyroid hormone. Am. J. Physiol. 1990, E278-E283.
  • Damm Jørgensen, K., Svendsen, 0., Agergaard, N., and Skydsgaard, K.: Effect of Human Growth Hormone on the Reproduction of Female Rats, Pharmacol. Toxicol. 1991, 68, 14-20.
  • Flyvbjerg, A., Jørgensen, K.D., Marshall S.M. and Ørskov, H.: Inhibitory effect of octreotide on growth hormone induces insulin-like growth factor I. generation and organ growth in hypophysectomized rats. Am. J. Physiol., 1991, 260 , E568 -E574.
  • Bjørn-Hansen Götzsche, L.S., Flyvbjerg, A., Marshall, S., Damm Jørgensen, K., and Weeke, J.: The influence of Growth Hormone and Thyroxine on lodothyronine Deiodinase Activity in Liver, Kidney and Brown Adipose Tissue in Hypophysectomized Rats. Acta Endocrinol (Copenh) 1991, 125, No 2, 219-226.
  • Marshall, S.M., A. Flyvbjerg, K.D. Jørgensen, J. Weeke and H. Ørskov.: Effects of growth hormone and thyroxine on kidney insulin-like growth factor-I and renal growth in hypophysectomized rats. Journal of Endocrinology (1993) 136, 399-406.
  • Ellegaard, L., Jørgensen, K.D., Klastrup, S., Kornerup Hansen A. and Svendsen, 0.: Haematologic and clinical chemical values in 3 and 6 months old Göttingen minipigs. Scand. J. Lab. Anim. Sci. No. 3,1995, Vol. 22,239-248.
  • Damm Jørgensen, K., Ellegaard, L., Klastrup, S. and Svendsen, 0.: Haematological and Clinical Chemical Values in Pregnant and Juvenile Göttingen Minipigs. Scand. J. Lab. Anim. Sci., Vol, 25, (Suppl. 1), 181-190, 1998.
  • Damm Jørgensen, K., Kledal, T.S.A. Svendsen, 0. and Skakkebæk, N.E.: The Göttingen Minipig as a Model for Studying Effect on Male Fertility. Scand. J. Lab. Anim. Sci., Vol. 25, (Suppl. 1), 161-169, 1998
  • Damm Jørgensen, K.: Minipig in Reproduction Toxicology. Scand. J. Lab. Anim, Sci., Vol. 25, (Suppl. 1), 63-75,1998
  • Damm Jorgensen, K.: Teratogenic Activiry of Tretinoin in the Göttingen Minipig. Scand, J. Lab. Anim. Sci., Vol. 25, (Suppl. 1), 235-243,1998
  • Svendsen, O., Hansen, H.B. and Damm Jørgensen. K.: Significance of injection solution temperature on local muscle tissue damage in pigs. Pharmacology and Toxicology, 38, 301-303, 1998.
  • Svendsen, O., Hansen, H.B. and Damm Jørgensen. K.: Injektionsskader og temperatur af injektionsmedicin. DS nyt (danske sIagterier), marts 1998, pp 28-29 and Dansk Veterinærtidsskrift, 15 pp 2-', 1998.
  • Svendsen, O., Andersen, H.V., Damm Jørgensen. K. and Klastrup, S. : Haematology in mice after weekly blood sampling for 7 weeks, Scand.J. Lab. Anim.Sci., No 1, 1998, Vol. 25,13-15.
  • Agersø, H., Wilken. M., Drustrup, J., Haahr, P. M. and Damm Jørgensen, K.: Plasma concentration of hGH and anti-hGH antibodies after subcutaneous administration of hGH for 3 weeks to immunosuppressed pigs. J. Pharrnacol Toxicol 41 (1999) 1-8.
  • Bollen, P.J.A., Madsen, L.W., Jørgensen, K.D. and Ritskes-Hoitinga, J.: Ad libitum feeding of Göttingen minipigs with two types of diet - a pilot experiment. FELASA Proceedings, May 1999.
  • Kledal, T.J.S., Raipert-De Meyts, E., Skakkebæk, N.E. and Damm Jørgensen, K.: A Dose-Finding Study of in utero and Lactational Exposure to Diethylstilboestrol and Flutamide in 129/Sv Mice. In press: Pharmacology & Toxicology 87 ( 2000).